Common typology, architecture, and structural features of the “DMT world” included descriptions of alternate or higher dimensions (n = 952, 25.2%) rooms, and a tunnel (n = 390, 10.3%). A companion-type, pedagogical, or guide-type interaction was identified 32.4% of encounters (n = 557). Entity interactions were predominantly positive (n = 600, 34.9% of encounters) involving benevolent, comforting, protecting, or outwardly caring interactions. Entity encounters were reported in 45.5% (n = 1719) of the experiences and involved predominantly a feminine phenotype (n = 416, 24.2%) deities (n = 293, 17.0%) aliens (n = 281, 16.3%) creature-based entities (n = 158, 9.2%, including reptilian and insectoid beings) mythological beings (n = 144, 8.4%, including machine elves) and jesters (n = 112, 6.5%). Visualizations predominantly consisted of fractals, shapes, patterns (n = 1231, 32.6%) and vivid colours (n = 953, 25.2%). The most common somatic effects were somaesthesias (n = 1415, 37.5%) and an auditory ringing (n = 583, 15.4%). A median dose of N, N-DMT of 40.0 mg and a median experience duration of 10 min (IQR, 5.0 to 15.0) were identified. A total of 3778 experiences from 3305 posts were included in this study. A qualitative analysis was conducted of all N, N-DMT experiences posted to the r/DMT Reddit community over a 10-year period from 2009 to 2018. Understanding the phenomenology and content of the inhaled N, N, dimethyltryptamine ( N, N-DMT) experience is critical to facilitate and support ongoing research and therapeutic models targeting mental health conditions and central nervous system pathology.
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